UPDATE: Wow, this time it works Retro! I re-did the setup and changed "Use All Controllers" then it worked. So, now I have a consistent way to exit emulators. Not sure why this option "Use All Controllers" was needed in BigBox but it seemed to fix it. I now have my first emulator fully working exactly how I want. My next test is to see if this thing will even run on the POS Dreamcade Reply. I also have to figure out if SNES games are saving. They do not appear to be saving and always start from scratch.
Thanks Retro, I agree, seems very odd. I will go through again and try All Controls. As I remember, the other controller buttons worked in the interface but nothing from Controler Automation (i.e. Vol Up/Down did not work either).