I just had this problem and came here to figure out what was going on and found this thread... I have almost all corsair hardware and sometimes Corsair Utility Engine sort of freezes. When this happens, your keyboard and mouse etc. still works, but "little things" stop working and you may not notice right away. Things like num lock and caps lock wont work, thumb buttons on the mouse and any macros or remaps stop working as well - Stuff the Corsair software is handling. It's happened several times, but this is the first instance where I've seen it conflict with another piece of software (causing launchbox options and bigbox to not load). I would have never put the two issues together until I found this. Luckily it's an easy fix if it ever does happen. You don't even have to restart Corsair Utility Engine, although that's obviously where the root of the problem is lying - just unplug and re-plug your keyboard and mouse, CUE automatically re-identifies the hardware and it snaps out of it's freakout.