BigBox Controller Issue, But Not In Launchbox

[djtripnosis]

I'm having a very strange issue. Using Launchbox premium on a Win10 PC. When I launch any game using Retroarch in Launchbox, everything works correctly. If I do the same from BigBox, when I try to access the Retroarch menu, either with controller combo or F1, Retroarch then loses all input. Controller, keyboard and mouse. I have to force close Retroarch to get control of any kind back. Again, this only happens in BigBox. It works just fine if I launch the same game from Launchbox.
Using Xbox360 Wireless Controller, XInput.

Any ideas?

(Edited to add a video showing the issue)

Edited May 7, 2022 by djtripnosis