I figured out another solution, but much thanks! What I did is copy the files in my lair folder (m2v, ogg, txt frame file) into a new folder, and I named the folder after the rom I wanted to run ( in this example, those files were copied to a folder named dle21). Then, I also renamed my txt frame file to match the rom name as well (so dle21.txt in this case). Then, I added the new txt file as a separate rom under my daphne category in launchbox. Again, I'm following the ETAPrime video where he added daphne roms using the frame files and a bat file to run the emulator. This process worked for getting dragon's lair enhanced working, and it worked for the space ace enhanced rom (sae) as well using the same process.
If you're good as syslinking files you can probably save some memory syslinking the video and audio files but I just copied them over instead.