Hello, in case anyone sees this and needs help with CXBX Reloaded, this is what worked for me with the most recent version of the emulator as of right now:
The emulator auto loads the game now as long as you point Launchbox to the default.xbe file
There is also an alternative you can use if you want to compress the game's files. All you do is either rename the default.xbe to default.cue OR you can copy the default.xbe file and paste it in the same directory and rename it ANYTHING.cue All that matters is that the file extension is CUE and launchbox will send it to the emulator and it will automatically load.
As far as making it go fullscreen and being able to exit, this script works for my system:
Sleep, 3000
Send !{enter}
$Esc::
{
Send {f6}
Send !{f4}
Return
}
Put it in the Running AutoHotKey Script tab and you're good to go!
***Unless things work for you, be sure that the emulator's Video config settings has Use Exclusive Fullscreen Mode UNCHECKED ***
On my system that causes issues and the game screen goes black and the emulator won't close without using Task Manager to End Task.
Hope that all makes sense and helps someone!