Thanks for your comment. I probably should have clarified that I don't have a RetroArch install in a default named folder.
Each install folder name includes the name of the video driver, configured controller and sometimes core.
Still, running the RetroArch update in LB did update at least one of my installations.
Years ago, I asked one of the RA devs about using custom config files for specific controller (M30, SN30 Pro+, Arcade stick, and various OG controllers with Raphnet adapters), button mapping and driver settings. I don't remember the exact combination of features that caused the issue but I was told it would not work the way I wanted and I should use separate RA folders for each config.