Sorry for any confusion in my earlier posts - I got everything working exactly the way I wanted it to work using the AHK scripts. I had already been using Demulshooter, but even if you are using Demulshooter, my understanding is that you have to set the UserRawInput setting in the EMULATION.INI file to 1 if you want to use two light guns, because only if this setting is set to 1 will the Model 2 emulator recognize 2 mice, or 2 lightguns if you are setting them up as such. If you set the RawUserInput setting to 1, I think it disables the ability to use XBOX 360 controllers, so you can't switch from gun games using 2 guns to fighting games using an Xbox controller without changing settings in the EMULATOR.INI file. Using the AHK script that Headrush69 provided in his initial response, I set up 2 exe files to use for gun and fighting games, and added these exe files as additional applications in Launchbox. I thought about exploring the 2 emulator option, but I like all my Sega Model 2 games being listed under the same emulator in launchbox. Now everything runs seamlessly. I can pick up my Harmony remote, turn on my system, use the same remote to select the game, and then just start shooting or fighting. It can be tedious, but setting up launchbox is kind of cool.