Yeah, I got it working now at mostly 60 FPS by enabling the Alpha hack and setting skipdraw from 2 to 4. I also set EE cyclerate to 130% EE cylce skip to mild. Enabling MTVU on my Ryzen also helped. Now it works!
I'll just list all my PS2 iso's that doon't have a config yet here. Would be cool if they would be added to the list
Beyond Good and Evil
Black
Devil May Cry 2
Digimon World 4
Digimon World Data Squad
Budokai Tenkaichi 3
Dynasty Warriors 5
Enter the Matrix
Full Metal Alchemist 2
The Godfather
GTA Liberty City Stories
GTA Vice City Stories
Grandia II
Gungrave
Jak 2
Jak 3
Kingdom Hearts II
Matrix Path of Neo
Mega Man X Collection
Metal Gear Solid 2 Sons of Liberty
Monster Rancher 3
Ninja Assault
Red Dead Revolver
Resident Evil 4
Return to Castle Wolfenstein
Socom
Syphon Filter Dark Mirror
Syphon Filter Logans Shadow
Syphon Filter The Omega Strain
Tenchu Fatal Shadows
Timesplitters 2
Timesplitters Future Perfect
TH Underground 2