Ah, I see. Xpadder will do this for you, yes, but you'll need some custom configuration help in order to pull it off. Basically, you can add an additional app to LaunchBox that fires immediately before the game is run to enable a specific Xpadder profile per game. It should great but might not be the easiest thing to set up. We still plan to tackle a controls mapping solution like that ourselves, but it isn't the highest priority, so unfortunately it will probably be a while still.