This is my DeSmuME "Running Hotkey Script" to go full screen and exit with ESC or by pressing L3:
WinWaitActive , DeSmuME ;
Send !{Enter}
$Esc::
{
Process, Close, {{{StartupEXE}}}
}
$joy9:: ; my L3 button
{
keywait, joy9, t2
if errorlevel <> 0
{
Process, Close, {{{StartupEXE}}} ;closes emulator
}
}
Note if nothing is going full screen with it, you just need to set it full screen once in a game and exit and I think it remembers is the next time, the script above may just be for ways to exit it.